Laying Out Structural Biology & Biophysical Approaches to Undergo Functional Characterization of AUTOTAC Induced Proximity Therapies
1:30 pm - Thursday 10th December 2026
- Unlocking insights from structural and biophysical and characterization to design and optimize AUTOTAC constructs that facilitate multi-protein assembly
- Describing early functional characterization of selective binding of autophagy-targeting ligand to ZZ domain of the archetypal autophagy cargo receptor p62/SQSTM1
- Laying out experimental validation from AUTOTAC discovery through ongoing preclinical and clinical-stage development of pipeline candidates